Frequently Asked Questions
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Olfactive Biosolutions repurposes food molecules, utilizing ectopic receptors to elicit physiological benefits comparable to drugs.
This innovative approach explores the potential of olfactory, taste and ectopic receptors in harnessing therapeutic effects of common food, beverage and fragrance ingredients.
Olfactive Biosolutions uses its TruePath Receptor Platform for this work, and to offer solutions to customers for malodor removal, especially in recycled plastics, and to quantitatively measure taste and smell for the food & beverage, consumer packaged goods, ingredients and flavor and fragrance industries.
Protenx is a line of products that comprise proprietary formulations of food, beverage or fragrance molecules.
These formulations are designed to activate ectopic receptors in the gut and elsewhere to provide beneficial physiological effects such as GLP-1 and GIP secretion for potential weight loss and blood sugar reduction. Other Protenx formulations correlate ingredients to receptor activity that releases neurotransmitters such as serotonin and thus potentially help to relieve anxiety or depression.
Olfactive Biosolutions sells these formulations to food and beverage and consumer packaged goods companies for inclusion in their products, such as snacks, bars, coffee and other products.
Olfactive Biosolutions is not an eNose. We are using biology - the olfactory, taste and TAAR receptors from the nose and tongue and ectopic receptors from throughout the body.
eNose companies use varying types of analytical chemistry technology such as surface plasmon resonance, surface acoustic wave, mass spectrometers or gas chromatography.
These technologies can be good at detecting chemicals but don't tell you what Coca-Cola tastes like or how Chanel No.5 smells, because they do not intersect with the human perception pathway. They do not give you an understanding of how ectopic receptors affect various physiological pathways.
Olfactive Biosolutions sells its Protenx line of proprietary health and wellness formulations to large food and beverage and consumer packaged goods companies for new product development and inclusion in existing products.
We also offer services working with flavor, aroma, scent, malodor and off-tastes such as bitterness. Especially in plastics recycling, persistent malodors are a barrier to widespread adoption.
AI without the right data doesn't get you much. AI without actual olfactory, taste and ectopic receptor data cannot tell you much about human perception or receptor-mediated physiology.
To date other companies attempting to use AI to create new consumer products or reformulate existing products have not been very successful. Olfactive Biosolutions has the potential to combine artificial intelligence with unique taste and smell data to transform entire industries.
Olfactive Biosolutions combines its unique knowledge of odorant and tastant molecules, and how they interact with olfactory or taste receptors to generate a specific perception, with artificial intelligence and large language models (LLM). This application of advanced AI to biology has the potential to disrupt radically the food & beverage, consumer packaged goods and ingredients industries.
Until now there has been limited progress on directly training artificial intelligence models using human olfactory, taste and ectopic receptor data. Our sensory systems are highly complex and involve intricate interactions between receptors, molecules, and the brain.
Developing AI models that can truly simulate human olfactory and taste perceptions requires a deep understanding of the biological processes involved and complex interactions between receptors and molecules.
We use the actual olfactory and taste receptors in our sensing lab to produce large amounts of sensory data and use that to train our AI algorithms.
Our system uses light as the secondary messenger. The intensity of a receptor response is measured by plate readers which capture the light expressed by the receptor. We generally need 1 to 5ml of the analyte depending on the format.
Our TruePath Receptor Platform sensing system uses the actual olfactory, taste, TAAR, ectopic and TRP channel receptors from the nose and tongue and throughout the body. It closely mirrors the human olfactory system in sensitivity. Studies also show achievement of a lower ppm of detection when compared with gas chromatography.
We can recommend molecules to shift the perception towards the target perception.
We can recommend volumes to shift the perception towards the target perception.
Generally yes, and without human or animal involvement. We offer malodor detection, measurement & cancellation: interrupting the odor communication chain to effectively eradicate bad odors or off-tastes.
We provide the range of receptor activity, including which receptors respond, how weakly or strongly, and which receptors are likely suppressing or amplifying other receptors.
We are currently researching which food or fragrance molecules dock with olfactory, taste and ectopic receptors to cause release of neurotransmitters such as serotonin that induce certain emotions or moods.
TAARs are also a class of chemosensory receptors that play a role in odorant sensing. They follow the same canonical pathway as olfactory receptors, and are also expressed in the olfactory epithelium as well as peripheral tissues. They however distinctly respond to volatile trace-amines which are associated with malodor or heat sensations.
Olfactive Biosolutions can provide a solution to objectively measure and fix taste and bitterness problems in your products and prototypes, without animal or human testing.
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