Replacing Pharmaceuticals With Food Molecules

Repurposing Food Molecules to Achieve the Same Health Effects as Weight Loss Drugs and More With Pivit™

Olfactive Biosolutions Granted Patent for Next-Generation Daily Weight Loss Pill; Pivit™ is the First-to-Market Effective Daily Nonprescription Pill for Weight Loss

Pivit is a Natural Triple Receptor Agonist That Works by Increasing Three Hunger-Regulating Hormones: GLP-1, PYY and GIP

Available September 2025 as a Direct-to-Consumer Supplement and as a Food Ingredient

MOUNTAIN VIEW, Calif.--(May 6, 2025)--Olfactive Biosolutions, the leader in adapting food molecules to treat chronic diseases, was today granted a patent for formulations of food molecules that cause significant weight loss when taken as a daily pill. The company’s Pivit supplement induces the simultaneous secretion of GLP-1, PYY and GIP, in U.S. patent US 12,290,550, Compositions for Treating Endocrine Diseases and Disorders. The company now has four granted patents that cover weight loss and blood sugar regulation.

Pivit™ is Making Waves in Consumer Trials

"Lack of hunger... feeling a lack of interest in food"

"Lost 3.3 lbs in 7 days... 15 lbs in 14 days."

"Blood sugar level went down to average of around 98 mg/dL from 110-123 mg/dL."

"Completely turned off food noise... eliminated after-dinner snacking."

Transforming Health & Wellness with Olfactory, Taste and Ectopic Receptors

Olfactory and taste receptors in the nose and tongue let us smell and taste the world. These receptors also exist elsewhere in the body, where they are generally known as ectopic receptors. Ectopic receptors play roles including regulating glucose and lipid metabolism, influencing insulin and glucagon secretion, fatty acid processing, and thermogenesis. Olfactive Biosolutions and its Pivit line of products are using food molecules to activate ectopic receptors in the body to replace pharmaceuticals.

Beneﬁts of Pivit Patented Formulations of Food Molecules vs. Pharmaceuticals:

Cost-Effective: Food molecules are often more affordable than pharmaceutical drugs, making them accessible to a wider population.

Low Risk of Side Effects: In contrast to pharmaceutical drugs, which often have a range of side effects, food molecules are generally safer and elicit minimal adverse reactions when consumed in appropriate amounts.

Natural Ingredients: Food molecules are derived from natural sources such as fruits, vegetables, grains, spices and herbs, making them more readily accepted by the body compared to synthetic pharmaceuticals.

Nutrient-Rich: Many food molecules promote overall health and well-being by containing essential nutrients, vitamins, minerals, antioxidants, and phytochemicals.

Proven Science: We hold numerous patents using food ligands to affect ectopic taste, olfactory and related receptors in order to treat diseases, including:
• U.S. patent 12,115,134, Compositions and Methods for Treating Endocrine Diseases and Disorders, shows methods to induce the secretion of GLP-1.
• U.S. patent 12,102,664, Compositions and methods for Treating Endocrine Diseases and Disorders, shows methods to induce the dual secretion of GLP-1 and GIP.
• U.S. patent 12,171,727, Compositions and methods for Treating Endocrine Diseases and Disorders, shows further methods to induce the dual secretion of GLP-1 and GIP.
• U.S. patent 12,102,611, Compositions and Methods for Treating Hypertension by Modulating Endocrine Activity.
• U.S. patent 12,186,299, Compositions and Methods for Treating Hypertension by Modulating Endocrine Activity.

We have additional patents pending for treating a number of chronic conditions.

Weight Loss Powered by Pivit

One example of using formulations of food molecules with ectopic receptors is for weight loss and blood sugar regulation.

Modern weight loss drugs are edited versions of GLP-1, a naturally occurring molecule. These edits make it last longer in the body, enhancing weight loss and blood sugar effects. Patients inject the modified GLP-1.

In our case, the consumer will ingest a formulation of food molecules -- one of the Pivit line of proprietary formulations -- that has been added to a product like coffee, energy bar, sports drink, or cookies, or take the formulation as a supplement.

Scientists tune the formulation to activate an ectopic receptor in the gut, specifically OR51E1, which then causes the generation of natural GLP-1.

Natural GLP-1

Natural GLP-1 doesn't endure as the pharmaceutical version does, but by activating the OR51E1, patients receive consistent GLP-1, mirroring the effects of the weight loss drug minus potential side effects. Unlike the edited drug molecule, the food molecules we use have been part of human diets for millennia.

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Naturally Prolonging the Effect

OR51E1 remains active as long as it has access to the appropriate food molecules in our formulation. In time, we can tune the formulation to persist in the gut for as long as we need the increased GLP-1 levels.

This same approach applies to GIP (GIP is a naturally occuring molecule that has many of the same effects as GLP-1.)

We believe the same approach can induce desired physiological benefits in many areas, including reducing inflammation, increasing bronchodilation, muscle mass, and bone remodeling.

Partnering Opportunities

Pivit Weight Loss formulation will be available direct to consumers in June 2025.

Pivit patented formulations are available for license now to food and beverage, consumer packaged goods, ingredients and health and wellness companies. Please contact us at sales@olfactive.bio.